13 Oct Establishing a clinical trial centre for vaccine research
Dr Goldenberg shares how establishing a clinical trial centre for the vaccine was the “most interesting, challenging and rewarding” project of his career....
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23 Nov Alzheimer’s Disease Linked to High Cumulative Doses of Zolpidem in Elderly
High cumulative doses of zolpidem are associated with a greater risk for developing Alzheimer disease (AD) in elderly patients, according to a retrospective study published in the Journal of the American Geriatric Society....
23 Nov Predicting Alzheimer Dementia Risk With CSF, MRI Clinical Biomarker
The use of clinical biomarkers obtained from cerebrospinal fluid (CSF) and magnetic resonance imaging may be effective for predicting risk for and aiding in the clinical decision-making of Alzheimer disease (AD) dementia, according to study findings published in JAMA Neurology....
23 Aug Growing Old Without Alzheimer’s Pathology: What’s the Secret?
It may be possible to grow old without developing Alzheimer’s disease pathology (ADP), although a wide range of very different types of protective factors are involved. A study published in JAMA Neurology looked at the differences in patterns of amyloid deposition and neurodegeneration that comprise ADP and found that, although challenging, “exceptional aging” without ADP is achievable.1...
23 Mar Diagnosing Depression in Dementia: Available Tools
Results from a systematic review and meta-analysis examining tools to detect depression in dementia show that tools incorporating collateral histories as well as a clinician interview with the patient, such as the Cornell Scale for Depression in Dementia (CSDD) or the Hamilton Depression Rating Scale (HDRS), have higher sensitivity for detecting depression, thus reducing false negatives....
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